Paul I. Terasaki, PhD, 1929-2016.

The Special Issue on Immunobiology of Transplantation

perspective. Five of them were conceived and written under the leadership of Paul I. Terasaki, one of the pioneers in the development of organ transplanation, who is well known for a wide array of contributions to the field of immunobiology of transplantation. First, he developed the cytotoxicity assay to match donors to recipients [4], exposing donor HLA-expressing cells to the recipient’s ser...

Immunobiology of Allograft Human Leukocyte Antigens in the New Microenvironment

β2m: β2-Microglobulin; β2m-free HC: β2m-free Heavy Chain; CTL: CD8+ Cytotoxic T Lymphocytes; DSA: Donor Specific Antibodies; HC: Heavy Chain Polypeptide; HLA: Human Leukocyte Antigens; HLA-I: Human Leukocyte Antigen Class I; HLA-II: Human Leukocyte Antigen Class II; IFNγ: Interferon-γ; kDa: kilodalton; MHC: Major Histocompatibility Complex; MMP: Matrix Metalloproteinase; rHLA: Recombinant HLA; ...

Males: Pattern of HLA-Ia Reactivity of Anti Antibodies to HLA-E in Nonalloimmunized

Is ABO-Compatible but Non-Identical Intestinal Transplant Comparable to ABO-Identical Transplant? An Analysis of the UNOS Registry

Junchao Cai1*, Xin Qing2, Guosheng Wu3, Matthew Everly1, Elaine Cheng1,4, Paul Terasaki1 1Terasaki Foundation Laboratory, Los Angeles, CA, United States 2Department of Pathology, Harbor-UCLA Medical Center, Torrance, CA, United States 3Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi’an, China 4Department of Surgery, UCLA Medical School, Los Angeles, CA, United ...

Immunobiology of HLA Class-Ib Molecules in Transplantation

APC: Antigen-Presenting cells; β2m: Beta2-Microglobulin; BMT: Bone Marrow Transplantation; DSA: Donor-Specific Antibody; ER: Endoplasmic Reticulum; GvHD: Graft-versus-Host Disease; HLA: Human Leukocyte Antigen; HSCT: Hematopoietic Stem Cell Transplantation; IFN: Interferon; ILT2: Ig-like Transcript 2; ILT4: Ig-like Transcript 4; MHC: Major Histocompatibility Complex; MLR: Mixed Lymphocyte React...